Article
Plasmodium falciparum: correlation of in vivo resistance to chloroquine and antifolates with genetic polymorphisms in isolates from the south of Lao PDR.
Tropical medicine & international health : TM & IH - 1 Sept 2003
Berens Nicole, Schwoebel Babett, Jordan Sabine, Vanisaveth Viengxay, Phetsouvanh Rattanaxay, Christophel Eva-Maria, Phompida Samlane, Jelinek Tomas
Abstract excerpt
Levels of drug resistance of Plasmodium falciparum strains against antimalarials have increased in Laos. In several studies, chloroquine (CQ) resistance has been associated with point mutations in the Pfcrt and pfmdr genes, and sulphadoxine/pyrimethamine (S/P) resistance with point mutations in t...
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