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Article

Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma.

Hepato-gastroenterology - 1 Jan 2000

Isa Tsutomu, Tomita Shuji, Nakachi Atsushi, Miyazato Hiroshi, Shimoji Hideaki, Kusano Toshiomi, Muto Yoshihiro, Furukawa Masato

Abstract excerpt

BACKGROUND/AIMS: Genetic alterations are considered to play an important role in both the carcinogenesis and biological behavior of human malignancies. However, the clinical implications of intrahepatic cholangiocarcinoma are poorly understood. We investigated the microsatellite instability, K-ras gene mutations and p53 protein overexpression and their correlation with clinicopathological features to elucidate...

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PMID: 12063950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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