Article
No evidence for BCL10 mutation in endometrial cancers with microsatellite instability.
Human mutation - 1 Feb 2001
Cohn D, Mutch D, Elbendary A, Rader J, Herzog T, Goodfellow P
Abstract excerpt
Previous reports have suggested that the mononucleotide repeats in BCL10 frequently are mutated in both hematologic malignancies and solid tumors. We set out to determine whether these repeats, like simple repeat sequences in other genes, are a target for mutation in endometrial cancers with defective DNA mismatch repair. Primary endometrial cancers (n = 42) and endometrial cancer cell lines (n=5) with...
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