Detection of base sequence changes in the CEBPD gene in human breast cancer cell lines and primary breast cancer isolates.

Abstract excerpt

Single strand conformation polymorphism (SSCP) analysis was performed on genomic DNA from 97 human breast cancer samples and 10 breast cell lines to screen for mutations in the single exon C/EBPD gene. Three C --> T transitions resulting in silent mutations were detected in three individual breast cancer samples. One breast cancer sample also contained a G --> T transversion (Q253H). The SUM-52PE cell line...

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