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Article

Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

The EMBO journal - 15 Feb 2001

Cantalupo G, Alifano P, Roberti V, Bruni C B, Bucci C

Abstract excerpt

Rab7 is a small GTPase that controls transport to endocytic degradative compartments. Here we report the identification of a novel 45 kDa protein that specifically binds Rab7GTP at its C-terminus. This protein contains a domain comprising two coiled-coil regions typical of myosin-like proteins and is found mainly in the cytosol. We named it RILP (Rab-interacting lysosomal protein) since it can be recruited...

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Topics

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11179213
DOI: 10.1093/emboj/20.4.683
PMCID: PMC145419

Genes

RILP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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