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Article

PKCepsilon activation induces dichotomous cardiac phenotypes and modulates PKCepsilon-RACK interactions and RACK expression.

American journal of physiology. Heart and circulatory physiology - 1 Mar 2001

Pass J M, Zheng Y, Wead W B, Zhang J, Li R C, Bolli R, Ping P

Abstract excerpt

Receptors for activated C kinase (RACKs) have been shown to facilitate activation of protein kinase C (PKC). However, it is unknown whether PKC activation modulates RACK protein expression and PKC-RACK interactions. This issue was studied in two PKCepsilon transgenic lines exhibiting dichotomous cardiac phenotypes: one exhibits increased resistance to myocardial ischemia (cardioprotected phenotype) induced by a...

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Source

Identifiers

PMID: 11179034
DOI: 10.1152/ajpheart.2001.280.3.H946

Genes

RACK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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