Article
Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
Journal of molecular biology - 9 Feb 2001
Fan J, Zhang Q, Tochio H, Li M, Zhang M
Abstract excerpt
Dyneins are multi-subunit molecular motors that translocate molecular cargoes along microtubules. Other than acting as an essential component of the dynein motor complex, the 89-residue subunit of dynein light chain (DLC8) also regulates a number of other biological events by binding to various proteins and enzymes. Currently known DLC8 targets include neuronal nitric oxide synthase; the proapoptotic Bcl-2 family...
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