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Article

Fusion genes in leukemia: an emerging network.

Cytogenetics and cell genetics - 1 Jan 2000

Bohlander S K

Abstract excerpt

The molecular analysis of recurring chromosome rearrangements, especially of translocations and inversions, has provided us with valuable insight into the pathogenesis of hematological malignancies. Many translocations result in the fusion of genes located at the translocation breakpoints. In recent years we have witnessed a rapid rise in the number of chromosome translocations in leukemias being characterized at...

Read the complete abstract on PubMed

Topics

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Share to Chromosome Breakage
Share to PDGFRB gene
Share to Leukemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasm Proteins

Share to Oncogene Proteins, Fusion

Share to Oncogenes

Share to Translocation, Genetic

Source

Identifiers

PMID: 11173830
DOI: 10.1159/000056818

Genes

ETV6
RUNX1
BCR
JAK2
PDGFRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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