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Article

Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways.

Annals of laboratory medicine - 1 Mar 2016

Marschalek Rolf

Abstract excerpt

Chromosomal translocations of the human mixed-lineage leukemia (MLL) gene have been analyzed for more than 20 yr at the molecular level. So far, we have collected about 80 direct MLL fusions (MLL-X alleles) and about 120 reciprocal MLL fusions (X-MLL alleles). The reason for the higher amount of reciprocal MLL fusions is that the excess is caused by 3-way translocations with known direct fusion partners. This...

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Share to Alleles
Share to Chromosomes, Human, X
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia

Share to Myeloid-Lymphoid Leukemia Protein

Share to Protein Structure, Tertiary

Share to Translocation, Genetic

Source

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Identifiers

PMID: 26709255
DOI: 10.3343/alm.2016.36.2.85
PMCID: PMC4713862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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