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The reciprocal world of MLL fusions: A personal view

12 Apr 2020

Abstract excerpt

Over the last 15 years the Diagnostic Center of Acute Leukemia (DCAL) at the Frankfurt University has diagnosed and elucidated the Mixed Lineage Leukemia (MLL) recombinome with >100 MLL fusion partners. When analyzing all these different events, balanced chromosomal translocations were found to comprise the majority of these cases (~70%), while other types of genetic rearrangements (3-way-translocations, spliced...

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Acute Myeloid Leukemia Research
Protein Degradation and Inhibitors
RNA Interference and Gene Delivery

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32294539
DOI: 10.1016/j.bbagrm.2020.194547

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