Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.

Neuron - 1 Apr 1994

Ignelzi M A, Miller D R, Soriano P, Maness P F

Abstract excerpt

The nonreceptor tyrosine protein kinases pp60c-src, p59fyn, and pp62c-yes are localized in growth cones of developing neurons, but their function is undefined. To determine whether these tyrosine kinases were capable of regulating substrate-dependent axon growth, cultures of cerebellar neurons from wild-type, src-, fyn-, and yes- mice were analyzed for neurite outgrowth on the neural cell adhesion molecule L1 or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Immunoblotting
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mutation

Share to Neurons

Share to Phosphorylation

Share to Protein-Tyrosine Kinases

Source

Identifiers

PMID: 7512817
DOI: 10.1016/0896-6273(94)90339-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.PMID 7512817Read ↗

p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway.Semantic proximity Read ↗

Src controls neuronal migration by regulating the activity of FAK and cofilin.Semantic proximity Read ↗

PTP1B regulates neurite extension mediated by cell-cell and cell-matrix adhesion molecules.Semantic proximity Read ↗

SRC-1, a non-receptor type of protein tyrosine kinase, controls the direction of cell and growth cone migration in C. elegans.Semantic proximity Read ↗

Absence of Fyn and Src causes a reeler-like phenotype.Semantic proximity Read ↗

Short- and long-term effects of LRRK2 on axon and dendrite growth.Semantic proximity Read ↗

L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region.Semantic proximity Read ↗

p75-deficient sensory axons are immunoreactive for the glycoprotein L1 in mice overexpressing nerve growth factor.Semantic proximity Read ↗

Identification of the border between fibronectin type III homologous repeats 2 and 3 of the neural cell adhesion molecule L1 as a neurite outgrowth promoting and signal transducing domainSemantic proximity Read ↗

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophySemantic proximity Read ↗

Ectopic expression of the neural cell adhesion molecule L1 in astrocytes leads to changes in the development of the corticospinal tract.Semantic proximity Read ↗

The neural cell adhesion molecule L1 potentiates integrin-dependent cell migration to extracellular matrix proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.