Article
Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment.
Neuron - 1 Dec 2000
Leiserson W M, Harkins E W, Keshishian H
Abstract excerpt
Fray is a serine/threonine kinase expressed by the peripheral glia of Drosophila, whose function is required for normal axonal ensheathment. Null fray mutants die early in larval development and have nerves with severe swelling and axonal defasciculation. The phenotype is associated with a failure of the ensheathing glia to correctly wrap peripheral axons. When the fray cDNA is expressed in the ensheathing glia...
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