Article
The Drosophila beaten path gene encodes a novel secreted protein that regulates defasciculation at motor axon choice points.
Cell - 13 Dec 1996
Fambrough D, Goodman C S
Abstract excerpt
In the Drosophila embryo, at specific choice points along the major motor nerves, subsets of motor axons defasciculate and then steer into their muscle target regions. Here we describe the analysis of beaten path (beat), a gene required for the selective defasciculation of motor axons at these ch...
Topics
- Amino Acid Sequence
- Animals
- Axons
- Cell Adhesion
- Cell Adhesion Molecules, Neuronal
- Chromosome Mapping
- Cloning, Molecular
- Connectin
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Genes, Insect
- Membrane Proteins
- Molecular Sequence Data
- Motor Neurons
- Muscle Proteins
- Muscles
- Mutagenesis