Article
Nervy links protein kinase a to plexin-mediated semaphorin repulsion.
Science (New York, N.Y.) - 20 Feb 2004
Terman Jonathan R, Kolodkin Alex L
Abstract excerpt
Cyclic nucleotides regulate axonal responses to a number of guidance cues through unknown molecular events. We report here that Drosophila nervy, a member of the myeloid translocation gene family of A kinase anchoring proteins (AKAPs), regulates repulsive axon guidance by linking the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) to the Semaphorin 1a (Sema-1a) receptor Plexin A (PlexA)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
