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Article

Stability engineering of antibody single-chain Fv fragments.

Journal of molecular biology - 2 Feb 2001

Wörn A, Plückthun A

Abstract excerpt

The application of single-chain Fv fragments (scFv) in medicine and biotechnology places great demands on their stability. Only recently has attention been given to the production of highly stable scFvs, and in a number of examples it was found that such fragments indeed perform better during practical applications. The structural parameters influencing scFv stability are now beginning to be elucidated. This...

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Identifiers

PMID: 11162109
DOI: 10.1006/jmbi.2000.4265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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