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Article

Rapid screening platform for stabilization of scFvs in Escherichia coli.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Miller Brian R, Glaser Scott M, Demarest Stephen J

Abstract excerpt

The poor biophysical properties of antibody fragments such as scFvs and diabodies can preclude their use as therapeutic agents. The non-ideal biophysical properties and insufficient thermal stability of antibody fragments often leads to poor expression, poor solubility, and a predisposition of th...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 19252856
DOI: 10.1007/978-1-59745-554-1_14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19252856-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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