Article
hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas.
Cancer research - 1 Aug 2000
Xinarianos G, Liloglou T, Prime W, Maloney P, Callaghan J, Fielding P, Gosney J R, Field J K
Abstract excerpt
DNA mismatch repair genes have been implicated in the pathogenesis and predisposition of certain malignancies through a mutator phenotype. In this study, we investigated, in 150 non-small cell lung carcinomas, the expression levels of hMLH1 and hMSH2 proteins in relation to loss of heterozygosity...
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