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Article

Rac1 regulates stress-induced, redox-dependent heat shock factor activation.

The Journal of biological chemistry - 10 Nov 2000

Ozaki M, Deshpande S S, Angkeow P, Suzuki S, Irani K

Abstract excerpt

The signaling pathway by which environmental stresses activate heat shock factors (HSFs) is not completely understood. We show that the small GTPase rac1, and Rac1-regulated reactive oxygen species (ROS) play an important role in stress-stimulated heat shock response. A dominant-negative allele o...

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Identifiers

PMID: 10952983
DOI: 10.1074/jbc.M005287200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10952983-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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