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Article

Transcriptional regulation of the small GTPase RhoB gene by TGFß‐induced signaling pathways

4 Nov 2009

Abstract excerpt

The purpose of the present study was to investigate the mechanism of transcriptional induction of the small GTPase RhoB gene by the transforming growth factor beta (TGFbeta) signaling pathway and the role of this regulation in TGFbeta-induced cell migration. To achieve our goals, we utilized a combination of siRNA-mediated gene silencing, adenovirus-mediated gene transfer receptor and MAPK inhibition,...

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PMID: 19890017
DOI: 10.1096/fj.09-134742

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