Article
Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells.
Experimental cell research - 1 Apr 2005
Mazières Julien, Tillement Vanessa, Allal Cuider, Clanet Carine, Bobin Lisbeth, Chen Zhi, Sebti Said M, Favre Gilles, Pradines Anne
Abstract excerpt
RhoB is a low molecular weight GTPase that is both farnesylated (RhoB-F) and geranylgeranylated (RhoB-GG) in cells. Based on data from rodent cell models, it has been suggested that RhoB displays differential effects on cell transformation, according to the nature of its prenylation. To test dire...
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