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Article

Evidence for a Graves' disease susceptibility locus at chromosome Xp11 in a United Kingdom population.

The Journal of clinical endocrinology and metabolism - 1 Feb 2001

Imrie H, Vaidya B, Perros P, Kelly W F, Toft A D, Young E T, Kendall-Taylor P, Pearce S H

Abstract excerpt

Graves' disease (GD), which has a strong female preponderance (female/male ratio, >5:1), is inherited as a complex genetic trait. Loci for GD have started to be defined using genome-wide approaches for genetic linkage. To date, 3 loci have been confirmed in at least 2 cohorts of GD patients, the strongest effect being at the cytotoxic T lymphocyte antigen-4 (CTLA-4) locus on chromosome 2q33 in our population. Two...

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Source

Identifiers

PMID: 11158020
DOI: 10.1210/jcem.86.2.7191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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