Article
Molecular biology of K(+) channels and their role in cardiac arrhythmias.
The American journal of medicine - 1 Jan 2001
Tristani-Firouzi M, Chen J, Mitcheson J S, Sanguinetti M C
Abstract excerpt
The configuration of cardiac action potentials varies considerably from one region of the heart to another. These differences are caused by differential cellular expression of several types of K(+) channel genes. The channels encoded by these genes can be grouped into several classes depending on the stimulus that permits the channels to open and conduct potassium ions. K(+) channels are activated by changes in...
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