Article
[Molecular biology of ion channels in the heart].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 2002
Matsuoka Tetsuro, Kurachi Yoshihisa
Abstract excerpt
Cardiac action potential is generated and maintained by several types of ion channels, such as sodium, calcium, potassium, chloride and non-selective cation channels. Mutation of cardiac ion channels could result in life-threatening arrhythmia. To date, the successful cloning of ion channels has revealed their molecular structure and function. Molecular biological and electrophysiological studies have developed...
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