Article
Heritable arrhythmias associated with abnormal function of cardiac potassium channels.
Cardiovascular research - 15 Jul 2020
Crotti Lia, Odening Katja E, Sanguinetti Michael C
Abstract excerpt
Cardiomyocytes express a surprisingly large number of potassium channel types. The primary physiological functions of the currents conducted by these channels are to maintain the resting membrane potential and mediate action potential repolarization under basal conditions and in response to changes in the concentrations of intracellular sodium, calcium, and ATP/ADP. Here, we review the diversity and functional...
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