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Article

Unscheduled DNA synthesis assay in mammalian spermatogenic cells: an update.

Environmental and molecular mutagenesis - 1 Jan 2000

Sotomayor R E, Sega G A

Abstract excerpt

The unscheduled DNA synthesis (UDS) assay measures DNA repair in response to DNA damage. To date, 59 chemicals plus UV and X rays have been tested for UDS in spermatogenic cells of humans, rabbits, rats, and mice. In vivo, in vitro, and combined in vivo/in vitro procedures have been used. UDS has been shown to occur in spermatogonia, meiotic spermatocytes, and early spermatid stages. Fifty-nine percent of the...

Topics

Animals
DNA Repair
Humans
Male
Mice
Mutagens
Mutation
Rabbits
Rats
Spermatozoa

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11152558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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