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Article

No association between tryptophan hydroxylase gene polymorphism and Alzheimer's disease.

Neuropsychobiology - 1 Jan 2001

Wang Y C, Tsai S J, Liu T Y, Liu H C, Hong C J

Abstract excerpt

Serotonergic dysfunction is implicated in Alzheimer's disease (AD) on the basis of studies of serotonin and its metabolite in postmortem specimens and CSF. There were also reports on association of a tryptophan hydroxylase (TPH) intron 7 variant and CSF 5-hydroxyindoleacetic acid concentrations. These suggested TPH might be a candidate to study for possible involvement in AD. Using a case-control association...

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Identifiers

PMID: 11150890
DOI: 10.1159/000054856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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