Tyrosine hydroxylase polymorphism in familial and sporadic Parkinson's disease.

doi:10.1002/mds.870090312

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Article

Tyrosine hydroxylase polymorphism in familial and sporadic Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 May 1994

Planté-Bordeneuve V, Davis M B, Maraganore D M, Marsden C D, Harding A E

Abstract excerpt

Tyrosine hydroxylase (TH) is a theoretical candidate gene determining susceptibility to Parkinson's disease (PD), and an association between one allele of a polymorphism at the TH locus and sporadic PD has been reported. We investigated TH polymorphism in 44 patients with sporadic PD, 48 patients...

Topics

Alleles
Chromosome Mapping
DNA
Gene Frequency
Genetic Carrier Screening
Genetic Linkage
Humans
Parkinson Disease
Polymerase Chain Reaction
Polymorphism, Genetic
Tyrosine 3-Monooxygenase

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