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Article

Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease.

Neuroscience letters - 31 May 2002

Orlacchio Antonio, Kawarai Toshitaka, Paciotti Eleonora, Stefani Alessandro, Orlacchio Aldo, Sorbi Sandro, St George-Hyslop Peter H, Bernardi Giorgio

Abstract excerpt

Serotonergic (5-hydroxytryptamine; 5-HT) transmission has been implicated in the pathogenesis of Alzheimer's disease (AD). A coding single nucleotide polymorphism 267 (C/T) in the 5-HT(6) receptor gene was previously reported as a susceptibility factor for AD. An extensive replication study was performed using our data set including sporadic and familial cases. No significant association between the 5-HT(6)...

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PMID: 12023056
DOI: 10.1016/s0304-3940(02)00221-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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