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Article

Heterogeneity in telomere length of human chromosomes

1 May 1996

Abstract excerpt

Vertebrate chromosomes terminate in variable numbers of T2AG3 nucleotide repeats. In order to study telomere repeats at individual chromosomes, we developed novel, quantitative fluorescence in situ hybridization procedures using labeled (C3TA2)3 peptide nucleic acid and digital imaging microscopy. Telomere fluorescence intensity values from metaphase chromosomes of cultured human hematopoietic cells decreased...

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Share to Advanced biosensing and bioanalysis techniques
Share to Chromosomal and Genetic Variations
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8733138
DOI: 10.1093/hmg/5.5.685

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