Article
Prospects for nutritional interventions in the clinical management of Fanconi anemia.
Cancer causes & control : CCC - 1 Dec 2000
Pagano G, Korkina L G
Abstract excerpt
The evidence associating Fanconi anemia (FA) phenotype to in-vitro and ex-vivo oxidative stress is reviewed. A cancer-prone genetic disease, FA is characterized by delayed bone marrow failure with a progression to aplastic anemia. It is diagnosed by excess chromosomal instability induced by two clastogens, either diepoxybutane (DEB) or mitomycin C (MMC). Clinical symptoms vary in a broad range including a...
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