Article
[Fanconi anemia--genotoxic stress and senescence of hematopoietic stem cells].
Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 2008
Yamashita Takayuki, Oda Tsukasa, Sekimoto Takayuki
Abstract excerpt
Fanconi anemia (FA) is a genetically heterogeneous inherited disorder characterized by progressive bone marrow failure, development of hematopoietic and solid malignancies and genomic instability. 13 FA proteins, identified to date, closely cooperate with familial breast cancer susceptibility proteins such as BRCA2 and PALB2, thereby forming 'the FA/BRCA molecular network'. Here I summarize our recent...
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