Article
DNA repair: exploiting the Fanconi anemia pathway as a potential therapeutic target.
Physiological research - 1 Jan 2011
Hucl T, Gallmeier E
Abstract excerpt
DNA repair is an active cellular process to respond to constant DNA damage caused by metabolic processes and environmental factors. Since the outcome of DNA damage is generally adverse and long term effects may contribute to oncogenesis, cells have developed a variety of DNA repair mechanisms, which operate depending on the type of DNA damage inflicted. At least 15 Fanconi anemia (FA) proteins interact in a...
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