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Article

The Drosophila genes disconnected and disco-related are redundant with respect to larval head development and accumulation of mRNAs from deformed target genes.

Genetics - 1 Jan 2001

Mahaffey J W, Griswold C M, Cao Q M

Abstract excerpt

HOM-C/hox genes specify body pattern by encoding regionally expressed transcription factors that activate the appropriate target genes necessary for differentiation of each body region. The current model of target gene activation suggests that interactions with cofactors influence DNA-binding ability and target gene activation by the HOM-C/hox proteins. Currently, little is known about the specifics of this...

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Identifiers

PMID: 11139504
DOI: 10.1093/genetics/157.1.225
PMCID: PMC1461496

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