Article
Isolation and characterization of the disconnected gene of Drosophila melanogaster.
The EMBO journal - 1 Apr 1991
Heilig J S, Freeman M, Laverty T, Lee K J, Campos A R, Rubin G M, Steller H
Abstract excerpt
Mutations in the disco (disconnected) gene prevent the establishment of stable connections between the larval optic nerves, the Bolwig's nerves, and their target cells in the brain during embryonic development. The failure of this initial connection is associated with aberrant development of the optic lobes which are largely degenerate in the mutant adult fly. In order to understand the role of disco in...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- Drosophila melanogaster
- Genes
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Restriction Mapping