Article
Drosophila embryos lacking N-myristoyltransferase have multiple developmental defects.
Experimental cell research - 15 Jan 2001
Ntwasa M, Aapies S, Schiffmann D A, Gay N J
Abstract excerpt
Lipid modification of proteins by the addition of myristic acid to the N-terminal is important in a number of critical cellular processes, for example, signal transduction and the modulation of membrane association by myristoyl switches. Myristic acid is added to proteins by the enzyme N-myristoyltransferase (NMT) and in this paper we detail the effects on embryonic development of a null mutation in the...
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