Article
Disruption of palladin results in neural tube closure defects in mice.
Molecular and cellular neurosciences - 1 Aug 2005
Luo Huijun, Liu Xuesong, Wang Fang, Huang Qiuhua, Shen Shuhong, Wang Long, Xu Guojiang, Sun Xia, Kong Hui, Gu Mingmin, Chen Saijuan, Chen Zhu, Wang Zhugang
Abstract excerpt
Palladin is a newly identified actin-associated protein which was proposed to be involved in actin cytoskeleton organization and nervous system development. Here, we show that inactivation of palladin leads to embryonic lethality due to severe defects of cranial neural tube closure and herniation...
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