Article

A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signalling

2020-02-05

Abstract excerpt

<h4>Summary</h4> Phosphoinositides (PI) are key regulators of cellular organization in eukaryotes and genes that tune PI signalling are implicated in human disease mechanisms. Biochemical analyses and studies in cultured cells have identified a large number of proteins that can mediate PI signalling. However, the role of such proteins in regulating cellular processes in vivo and development in metazoans remains...

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Literature Corpus work: 430c3c3c-f1ae-5c37-9042-e0661014466c
DOI: 10.1101/2020.02.03.933093

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