Article
Analysis of the role of HLA-G in preeclampsia.
Human immunology - 1 Nov 2000
O'Brien M, Dausset J, Carosella E D, Moreau P
Abstract excerpt
Preeclampsia (PE) is a multisystem disorder of human pregnancy, occurring in 5%-10% of all population births and represents the leading cause of both fetal and maternal morbidity and mortality in pregnancy. Although the disorder only becomes clinically apparent late in pregnancy, the underlying pathology indicates that invasion of fetal trophoblasts into maternal spiral arteries during early pregnancy is shallow...
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