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Article

A possible role for HLA-G in development of uteroplacental acute atherosis in preeclampsia.

Journal of reproductive immunology - 1 Apr 2021

Johnsen Guro M, Fjeldstad Heidi E S, Drabbels Jos J M, Haasnoot Geert W, Eikmans Michael, Størvold Gro L, Alnaes-Katjavivi Patji, Jacobsen Daniel P, Scherjon Sicco A, Redman Christopher W G, Claas Frans H J, Staff Anne Cathrine

Abstract excerpt

HLA-G, a non-classical HLA molecule expressed by extravillous trophoblasts, plays a role in the maternal immune tolerance towards fetal cells. HLA-G expression is regulated by genetic polymorphisms in the 3' untranslated region (3'UTR). Low levels of HLA-G in the maternal circulation and placental tissue are linked to preeclampsia. Our objective was to investigate whether variants of the 3'UTR of the HLA-G gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33578175
DOI: 10.1016/j.jri.2021.103284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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