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Article

Paternal contribution of HLA-G*0106 significantly increases risk for pre-eclampsia in multigravid pregnancies.

Molecular human reproduction - 1 May 2008

Tan Chia Yee, Ho Julia F V, Chong Yap Seng, Loganath Annamalai, Chan Yiong Huak, Ravichandran Jeganathan, Lee Caroline G, Chong Samuel S

Abstract excerpt

Pre-eclampsia (PE) is a leading cause of maternal and fetal mortality and morbidity. Structural or functional alterations of human leukocyte antigen (HLA)-G present at the maternal-fetal interface may predispose women to PE. We tested the HLA-G gene for association with PE in a case-control study of 83 PE and 240 normotensive Malay women. HLA-G was amplified in a single-tube multiplex-PCR reaction and genotyped...

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Source

Identifiers

PMID: 18353802
DOI: 10.1093/molehr/gan013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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