Article
Genetic analysis of insulin-like growth factor II and HLA-G in pre-eclampsia.
Biochemical Society transactions - 1 Feb 2000
Bermingham J, Jenkins D, McCarthy T, O'Brien M
Abstract excerpt
Pre-eclampsia (PE) is uniquely a disease of pregnancy and is the major cause of foetal and maternal morbidity and mortality. Epidemiological studies show that PE is highly heritable, with a high incidence in all populations. The underlying pathology indicates that absent or shallow invasion of foetal trophoblasts into maternal arteries is a feature of true PE. The objective of this study was to determine the...
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