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Transposase-Dependent Formation of Circular IS256Derivatives inStaphylococcus epidermidisandStaphylococcus aureus

1 Sept 2002

Abstract excerpt

IS256 is a highly active insertion sequence (IS) element of multiresistant staphylococci and enterococci. Here we show that, in a Staphylococcus epidermidis clinical isolate, as well as in recombinant Staphylococcus aureus and Escherichia coli carrying a single IS256 insertion on a plasmid, IS256 excises as an extrachromosomal circular DNA molecule. First, circles were identified that contained a complete copy of...

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Identifiers

PMID: 12169594
DOI: 10.1128/jb.184.17.4709-4714.2002

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