Article

The Insertion Sequence Excision Enhancer (IEE): a PrimPol-based system for Immobilizing Transposon-Transmitted Antibiotic Resistance Genes?

2023-06-07

Abstract excerpt

We provide an overview of a protein, IEE (Insertion Sequence Excision Enhancer), which was originally observed to facilitate high levels of excision of the IS3 family member, IS629, from clinically important Escherichia coli O157:H7. IEE was subsequently shown to affect a large class of bacterial insertion sequences which all transpose by producing a circular intermediate and presumably use the copy-out-paste-in t...

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Literature Corpus work: 04878c6e-3b7a-517d-872f-139c94dd45fd
DOI: 10.1101/2023.06.07.543989

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