Article
RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum.
Genes, chromosomes & cancer - 1 Feb 2001
Sakurada K, Furukawa T, Kato Y, Kayama T, Huang S, Horii A
Abstract excerpt
The retinoblastoma protein interacting zinc finger (RIZ) gene is a candidate tumor suppressor gene on 1p36, a region frequently rearranged in a wide variety of human tumors. As the RIZ gene harbors several microsatellites within its coding region, it is a candidate for an inactivating mutation in microsatellite instability (MSI) mediated carcinogenesis. In this study, we examined mutations of two poly adenine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
