Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between spindle assembly checkpoint expression and maternal age in human oocytes

1 Jan 2001

Abstract excerpt

The spindle assembly checkpoint modulates the timing of anaphase initiation in response to the improper alignment of chromosomes at the metaphase plate. If defects are detected, a signal is transduced to halt further progression of the cell cycle until correct bipolar attachment to the spindle is achieved. The mitotic arrest deficient (MAD2) and budding uninhibited by benomyl (BUB1) genes encode conserved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Chromatin Dynamics
Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11134360
DOI: 10.1093/molehr/7.1.49

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between spindle assembly checkpoint expression and maternal age in human oocytesPMID 11134360Read ↗

Age‐dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase BSemantic proximity Read ↗

Meiotic Origins of Maternal Age-Related Aneuploidy1Semantic proximity Read ↗

Gene expression profiles of single human mature oocytes in relation to ageSemantic proximity Read ↗

Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expressionSemantic proximity Read ↗

Why is Chromosome Segregation Error in Oocytes Increased With Maternal Aging?Semantic proximity Read ↗

Effect of maternal age on the frequency of cytogenetic abnormalities in human oocytesSemantic proximity Read ↗

Chromosome Abnormalities in the Human OocyteSemantic proximity Read ↗

Fertilization and early embryology: Influence of maternal age on meiotic spindle assembly oocytes from naturally cycling womenSemantic proximity Read ↗

Evidence That a Defective Spindle Assembly Checkpoint Is Not the Primary Cause of Maternal Age-Associated Aneuploidy in Mouse Eggs1Semantic proximity Read ↗

Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged miceSemantic proximity Read ↗

The meiotic competence of in-vitro matured human oocytes is influenced by donor age: evidence that folliculogenesis is compromised in the reproductively aged ovarySemantic proximity Read ↗

Chromosome Segregation in the Oocyte: What Goes Wrong during AgingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.