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Fertilization and early embryology: Influence of maternal age on meiotic spindle assembly oocytes from naturally cycling women

1 Oct 1996

Abstract excerpt

To examine the effects of maternal ageing on the meiotic apparatus, we obtained oocytes from naturally cycling women in two age groups, including younger (aged 20-25 years) and older (aged 40-45 years) women. Using high-resolution confocal microscopy we obtained a detailed picture of the meiotic spindle and chromosome placement during various phases of meiosis. Our data revealed that the meiotic spindle in older...

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PMID: 8943533
DOI: 10.1093/oxfordjournals.humrep.a019080

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