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Article

Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression

5 May 2010

Abstract excerpt

The ability to identify oocytes with the greatest potential for producing a viable embryo would be of great benefit to assisted reproductive treatments. One of the most important defects affecting oocytes is aneuploidy. Aneuploidy is also closely related with advancing maternal age, a phenomenon not well understood. This study combined a comprehensive cytogenetic investigation of 21 oocytes with a detailed...

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PMID: 20444854
DOI: 10.1093/molehr/gaq033

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