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Article

Oligomerization of DH domain is essential for Dbl-induced transformation.

Molecular and cellular biology - 1 Jan 2001

Zhu K, Debreceni B, Bi F, Zheng Y

Abstract excerpt

The dbl oncogene product (onco-Dbl) is the prototype member of a family of guanine nucleotide exchange factors (GEFs) for Rho GTPases. The Dbl homology (DH) domain of onco-Dbl is responsible for the GEF catalytic activity, and the DH domain, together with the immediately adjacent pleckstrin homol...

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Identifiers

PMID: 11134331
DOI: 10.1128/MCB.21.2.425-437.2001
PMCID: PMC86589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11134331-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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