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Article

LFA-1 expression on target cells promotes human immunodeficiency virus type 1 infection and transmission.

Journal of virology - 1 Jan 2001

Hioe C E, Chien P C, Lu C, Springer T A, Wang X H, Bandres J, Tuen M

Abstract excerpt

While CD4 and the chemokine receptors are the principal receptors for human immunodeficiency virus (HIV), other cellular proteins, such as LFA-1, are also involved in HIV infection. LFA-1 and its ligands, ICAM-1, ICAM-2, and ICAM-3, can be expressed on the cells infected by HIV, as well as on the HIV virions themselves. To examine the role of LFA-1 expressed on target cells in HIV infection, Jurkat-derived...

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Share to Cell Adhesion
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Share to Jurkat Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphocyte Function-Associated Antigen-1

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Share to T-Lymphocytes

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Source

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Identifiers

PMID: 11134324
DOI: 10.1128/JVI.75.2.1077-1082.2001
PMCID: PMC114007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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