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Article

The importance of virus‐associated host ICAM‐1 in human immunodeficiency virus type 1 dissemination depends on the cellular context

18 Jun 2004

Abstract excerpt

The primary objective of this study was to define whether the nature of virion-bound host cell membrane proteins influenced the process of human immunodeficiency virus 1 (HIV-1) capture and transmission. We pulsed cells of monocytoid lineage (established and primary) and CD4-negative epithelial cells transiently expressing DC-SIGN or LFA-1 with isogenic HIV-1 particles either devoid or bearing host-derived ICAM-1...

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PMID: 15208262
DOI: 10.1096/fj.04-1755fje

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